Jobbeschreibung
PhD Student (gn*) Biology, Biochemistry, Biomedicine, Experimental Medicine, Medicine Fixed-term of three years | Part-time with 65% (25 hours/week) | Salary according to TV-L E13 | Department of Anesthesiology, Intensive Care and Pain Therapy | Job ID: 10580 We are UKM. We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility. To meet our high standards every day, we are looking forward to your scientific expertise in the Department of Anesthesiology, Intensive Care and Pain Therapy - ideally with you on board! The Jorch Lab studies the mechanisms of immune cell activation and recruitment in various in vitro and in vivo models of inflammation and infections. In detail, this project addresses the functional analysis of PSTPIP1, a protein that is relevant in certain autoinflammatory diseases, and the alarmins S100A8/A9 in inflammasome activation using mainly biochemical and cell biological methods. This project provides an exciting and dynamic research environment with a broad range of state-of-the-art technologies from various departments, with excellent opportunities for networking and collaboration. Your Tasks Culture of immortalized cell lines Generation of mutant cell lines via CRISPR/Cas9 In vitro interaction studies with recombinant proteins and in vivo interaction studies using immortalized cell lines Functional assays including inflammasome activation, cytokine release, ROS production, phagocytosis, adhesion and migration What we expect: Master's degree in biology, biochemistry, biomedicine, experimental medicine, medicine or other related subjects/life sciences Strong knowledge in molecular biology, biochemical and immunological techniques such as western blot, flow cytometry, cell culture, ELISA Experience in working with mice or imaging techniques is not essential, but would be beneficial An independent, reliable and structured way of working with a focus on quality is essential Motivation , flexibility, good self-organization, and team working abilities Willingness to analyze and critically reflect scientific data Determination, profound knowledge and resilience to successfully complete the project and advance the scientific field Good written and spoken English language skills Strong interest in doing and understanding science Willingness to organize and prioritize work What we offer: Training, further development and working with state-of-the-art technologies in inflammation research Participation in and contribution to scientific group meetings, network meetings and conferences Encouragement and support for the preparation of research papers and scientific networking Excellent options for networking and collaboration through collaborative research networks An exciting and dynamic research environment Support for personal development and training Apply now via our career portal until 07.05.2025 including: A cover letter with a brief statement of research experience, research interests, research techniques, and career goals A CV with education certificates and grades Contact information of two possible referees (address, phone number and email) BENEFITS Exciting Projects Professional Development and Training Interdisciplinary Collaboration Part of Research Innovation Additional Benefits Exciting Projects Professional Development and Training Interdisciplinary Collaboration Part of Research Innovation Additional Benefits (*gn=gender neutral) The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them. Universitätsklinikum Münster Albert-Schweitzer-Campus 1, Gebäude D5 48149 Münster www.ukm.de
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