Jobbeschreibung
The University Hospital Heidelberg is one of the major healthcare centers in Germany. Our objective is the development of innovative diagnostics and therapies as well as their quick implementation for the patient. With about 14,000 employees in more than 50 specialized clinical departments with almost 2,500 beds, about 80,000 patients in part-time and full-time inpatient treatment as well as 1,000,000 patients in ambulant treatment are medicated each year.
PhD Student - Nephrology (m/f/d)
wanted from 01.06.2024 at the Center for Child and Adolescent Medicine for the Nephrology Lab.
In collaboration with the research networks TheraCil and Neocyst, the Center for Child and Adolescent Medicine Heidelberg is conducting a project that focuses on the research and treatment of rare genetic diseases, in particular renal ciliopathies. The aim of the project is to improve the diagnosis and prognosis of children with renal ciliopathies and to develop therapeutic approaches that target common pathological mechanisms. This project involves work on patient-derived renal organoids to decipher molecular signatures and develop therapeutic interventions that can modify the disturbed signaling pathways and cell functions.
- Job-ID: V000012587
- Field of application: Klinik Kinderheilkunde I (Allg. Pädiatrie, Neuropäd., Stoffwechsel, Gastroenterologie, Nephrologie)
- Location: Heidelberg
- Start date: 01.06.2024
- Job Category: Science and teaching
- Working hours: Part time (65 %)
- Limitation: Temporary (3 years)
- Contract: TV-L
- Working with human stem and progenitor cells and production of kidney organoids
- Characterisation of organoids using cell biological methods, immunohistochemical staining, confocal microscopy
- Genomic Analyses (i.e. RNA sequencing)
- Pharmacological Screening Methods
- Establishing new methods
- Successfully completed studies in biosciences, pharmacy or related discipline
- Interest in organoid-based model systems
- Ideally, you already have experience in cell culture work and are proficient in standard molecular biology methods (DNA, RNA and protein purification, PCR, Western Blot, etc.)
- Experience in bioinformatics techniques would be advantageous
- Interest in microscope-based imaging
- Above-average motivation, initiative, reliability and sense of responsibility
- Very good written and spoken English (knowledge of German is an advantage)
- Vaccination certificates according to §20 Infection Protection Act are available
- Working with the latest techniques / technical equipment
- Possibility of doctorate and possibility to publish scientifically is offered and supported
- Regular team meetings
- Collectively agreed remuneration, attractive company pension scheme (VBL)
- 30 days vacation
- Sustainable travel: job ticket
- Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
- Wide range of health, prevention and sports offers
Note: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.
The UKHD embraces diversity and values diversity.
Regardless of age, gender, sexual identity, disability, origin or religion, we offer everyone the same opportunities. If one gender is underrepresented in a particular area, we place particular emphasis on counteracting this imbalance. If they have the same aptitude, qualifications and professional performance, we give priority to people with severe disabilities when considering them for vacancies.